NF-κB-mediated enhancement of H3K27me3 through EZH2: a mechanism to suppress pyocyanin-induced autophagy in macrophages
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Medical Research"
DOI: 10.1186/s40001-025-02614-3
Abstract: Histone modification is a key mechanism of epigenetic regulation. Our previous study demonstrated that histone H3 acetylation at lysine 27 (H3K27ac) promotes pyocyanin (PYO)-induced autophagy in macrophages. However, the regulatory role of H3K27 trimethylation (H3K27me3)… read more here.
Keywords: pyo; induced autophagy; h3k27me3; ezh2 ... See more keywords
Synthesis of polypyrrole/cellulose nanocrystals disks for removal of pyocyanin metabolite biomarker released by Pseudomonas aeruginosa
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DOI: 10.1371/journal.pone.0327713
Abstract: Pseudomonas aeruginosa is a high-risk pathogen associated with several human diseases. Pyocyanin (PYO), a redox-active secondary metabolite produced by P. aeruginosa, plays a critical role in its survival and pathogenicity, exhibiting both antibacterial and toxic… read more here.
Keywords: pyo; cellulose nanocrystals; polypyrrole; pseudomonas aeruginosa ... See more keywords
Diagnosis and Stratification of Pseudomonas aeruginosa Infected Patients by Immunochemical Quantitative Determination of Pyocyanin From Clinical Bacterial Isolates
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DOI: 10.3389/fcimb.2021.786929
Abstract: The development of a highly sensitive, specific, and reliable immunochemical assay to detect pyocyanin (PYO), one of the most important virulence factors (VFs) of Pseudomonas aeruginosa, is here reported. The assay uses a high-affinity monoclonal… read more here.
Keywords: aeruginosa infected; pyo; pseudomonas aeruginosa; pyo ohphz ... See more keywords