Optimal interpretation of Tc99m PYP in 2020: Avoiding the million-dollar mistake
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DOI: 10.1007/s12350-020-02503-8
Abstract: The diagnosis of transthyretin cardiac amyloidosis (ATTR-CA) is now literally a million-dollar implication. With the approval of tafamidis (Vyndaqel/ Vyndamax) in 2019, ATTR-CA has become a treatable chronic disease state with potentially life prolonging therapy… read more here.
Keywords: interpretation; million dollar; cardiology; pyp imaging ... See more keywords
Imaging artifact and PYP imaging
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DOI: 10.1007/s12350-022-02929-2
Abstract: A 74-year-old white male was referred to the outpatient nuclear clinic by the advanced heart failure team with a history of CAD and HFrEF. Echo/Doppler exam revealed unexplained concentric thickening and an ‘‘apical sparing pattern’’.… read more here.
Keywords: pyp; pyp imaging; imaging artifact; cardiology ... See more keywords
SUV QUANTIFICATION OF 99MTC-PYP IMAGING IN TTR-CARDIAC AMYLOIDOSIS USING A CZT CAMERA: A NEW TOOL IN THE ARMAMENTARIUM
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DOI: 10.1016/s0735-1097(18)32230-7
Abstract: Transthyretin (TTR) cardiac amyloidosis (CA) is an increasingly recognized cause of heart failure. Diagnosis of TTR-CA relies on visual and semi-quantitative interpretation of planar 99mTc-PYP imaging. However, new methods that directly quantify PYP uptake may… read more here.
Keywords: pyp imaging; ttr cardiac; 99mtc pyp; cardiac amyloidosis ... See more keywords
Optimizing cardiac amyloidosis assessment: utility of 1-h and 3-h 99mTc-PYP imaging
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DOI: 10.1186/s40001-023-01629-y
Abstract: Transthyretin amyloid cardiomyopathy (ATTR-CM), characterized by the extracellular deposition of an insoluble amyloid protein in the heart, is one of the main causes of heart failure in elderly patients. In this study, our primary objective… read more here.
Keywords: heart; pyp imaging; incubation; cardiac amyloidosis ... See more keywords