An efficient synthesis of new polyfunctional hexahydro pyrido[1,2-a]pyrazin-1-ones
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DOI: 10.1016/j.mencom.2021.03.039
Abstract: New polyfunctional hydrogenated pyrido[1,2-a]pyrazin- 1-ones were obtained by regioselective recyclization of N-arylitaconimides with alkyl (3-oxopiperazin-2-ylidene)acetates. The supposed cascade reaction pathway involves the Michael addition of the nucleophile to an activated double bond and subsequent intramolecular… read more here.
Keywords: pyrido pyrazin; new polyfunctional; efficient synthesis; pyrazin ones ... See more keywords