Characterization of Thorium-Pyrazinoic acid complexation and its decorporation efficacy in human cells and blood.
Sign Up to like & getrecommendations! Published in 2021 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2021.129547
Abstract: Thorium (Th) exposure to the human beings is a radiochemical hazard and the chelation therapy by suitable drugs is the major prevention approach to deal with. The present studies aimed at usage of pyrazinoic acid… read more here.
Keywords: pyrazinoic acid; thorium; efficacy; decorporation ... See more keywords
Anti-Sporothrix brasiliensis activity of different pyrazinoic acid prodrugs: a repurposing evaluation
Sign Up to like & getrecommendations! Published in 2018 at "Brazilian Journal of Pharmaceutical Sciences"
DOI: 10.1590/s2175-97902018000417858
Abstract: *Correspondence: S. B. Waller. Centro de Diagnóstico e Pesquisa em Micologia Veterinária (MicVet), Departamento de Veterinária Preventiva, Faculdade de Veterinária, Universidade Federal de Pelotas (UFPEL). Rua Campus Universitário Capão do Leão, s/no, Prédio 1, 96010-900,… read more here.
Keywords: anti sporothrix; brasiliensis activity; pyrazinoic acid; sporothrix brasiliensis ... See more keywords
Molecular Specific and Sensitive Detection of Pyrazinamide and Its Metabolite Pyrazinoic Acid by Means of Surface Enhanced Raman Spectroscopy Employing In Situ Prepared Colloids
Sign Up to like & getrecommendations! Published in 2019 at "Applied Sciences"
DOI: 10.3390/app9122511
Abstract: The prodrug pyrazinamide (PZA) is metabolized by the mycobacteria to pyrazinoic acid (POA), which is expelled into the extracellular environment. PZA resistance is highly associated to a lack of POA efflux. Thus, by detecting a… read more here.
Keywords: enhanced raman; spectroscopy; pza; pyrazinoic acid ... See more keywords
A novel inexpensive electrochemical sensor for pyrazinoic acid as a potential tool for the identification of pyrazinamide-resistant Mycobacterium tuberculosis
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Mycobacteriology"
DOI: 10.4103/ijmy.ijmy_63_18
Abstract: Introduction: Tuberculosis (TB) is a significant cause of morbidity and mortality worldwide. The patient compliance with the long treatment regimens is essential for successful eradication. Pyrazinamide (PZA) shortens these regimens from 9 to 6 months,… read more here.
Keywords: pyrazinoic acid; tuberculosis; pza; electrochemical sensor ... See more keywords