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Published in 2017 at "Journal of Heterocyclic Chemistry"
DOI: 10.1002/jhet.2768
Abstract: In an attempt to find bio-active small molecules, a series of novel 3-(5-(3-(aryl)-1-phenyl-1H-pyrazol-4-yl)-1-phenyl-4,5-dihydro-1H-pyrazol-3-yl)pyridine 5a–i and 5-(3-(aryl)-1-phenyl-1H-pyrazol-4-yl)-3-(pyridin-3-yl)-4,5-dihydropyrazole-1-carbaldehyde 6a–i were designed, synthesized, and evaluated for their in vitro cytotoxic activity against a panel of human cancer cell…
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Keywords:
pyrazol;
aryl phenyl;
phenyl;
cell ... See more keywords
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Published in 2018 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/s10593-019-02409-5
Abstract: O-cyclialkylation of substituted bis[3-hydroxy-2-(pyrimidin-2-yl)-2H-pyrazol-4-yl]methane by α,ω-dibromoalkanes with a hydrocarbon chain length of up to three CH2 groups has been carried out. A novel pyrazolophane, 1,6-dioxacycloundecane with symmetrically annulated fragments of 1-(pyrimidin-2-yl)-1H-pyrazole, was isolated and characterized…
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Keywords:
pyrazol;
pyrimidin pyrazol;
substituted bis;
hydroxy pyrimidin ... See more keywords
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Published in 2017 at "Arabian Journal for Science and Engineering"
DOI: 10.1007/s13369-017-2530-2
Abstract: Series of novel 1,2-bis((3-(1-aryl-5-methyl-1H-1,2,3-triazol-4-yl)-1-phenyl-1H-pyrazol-4-yl)methylene) hydrazines 4 and 2-(5-(3-(1,2,3-triazol-4-yl)pyrazol-4-yl) pyrazol-1-yl)thiazoles 13 were synthesized using simple and convenient procedures, and their structures were established. Treatment of pyrazole-4-carbaldehydes 1 with methyl ketones in alkaline medium gave the corresponding…
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Keywords:
synthesis novel;
aryl methyl;
pyrazol;
gave corresponding ... See more keywords
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Published in 2017 at "Dalton transactions"
DOI: 10.1039/c7dt01153a
Abstract: Four new disubstituted and monosubstituted nitro- and amino- bis(pyrazol-1-yl)pyridine (bppy) ligands, substituted at the pyrazole 4-position (1, 2, 5, 6) have been synthesized, along with two luminescent Eu(iii) tris-β-diketonate derivatives of the amino substituted ligands…
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Keywords:
pyrazol;
pyrazol pyridine;
nitro amino;
luminescent iii ... See more keywords
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Published in 2023 at "Dalton transactions"
DOI: 10.1039/d3dt00735a
Abstract: The importance of electron deficient Tp ligands motivates the introduction of electron-withdrawing substituents into the scorpionate framework. Since perfluorophenyltris(pyrazol-1-yl)borate affects significant anodic shifts in half-cell potentials in their metal complexes relative those of phenyltris(pyrazol-1-yl)borate analogues,…
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Keywords:
pyrazol borate;
phenyl;
phenyltris pyrazol;
metal ... See more keywords