Polyfunctional pyrazoles 11*. Synthesis of 5-aroylpyrano[3,4-c]pyrazol-7(2H)-ones
Sign Up to like & getrecommendations! Published in 2017 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/s10593-017-2143-4
Abstract: Aroylmethyl esters of 4-formylpyrazole-3-carboxylic acids underwent intramolecular cyclocondensation in the presence of sodium acetate in refluxing acetic anhydride, giving moderate yields of 5-aroylpyrano[3,4-с]pyrazol-7(2Н)-ones. read more here.
Keywords: pyrazoles synthesis; aroylpyrano pyrazol; synthesis aroylpyrano; polyfunctional pyrazoles ... See more keywords
First synthesis and further derivatization of furo[3,2-c]pyrazol-6-ones
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2019.01.021
Abstract: Abstract For the very first time furo[3,2-c]pyrazoles have been prepared starting from pyrazole building blocks instead from furanes. During this synthesis effort two previously unknown heterocyclic scaffolds have been discovered, the furo[3,2-c]pyrazol-6-ones and the 2-cyano-3-aminofuran-4-ones. read more here.
Keywords: synthesis derivatization; pyrazol ones; furo pyrazol; first synthesis ... See more keywords
Organocatalytic diastereo- and enantioselective conjugate addition of pyrazol-3-ones to 3-trifluoroethylidene oxindoles with a newly developed squaramide catalyst
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DOI: 10.1039/d2ra05088a
Abstract: An efficient organocatalytic conjugated addition reaction of pyrazol-3-ones with 3-trifluoroethylidene oxindoles has been developed for the synthesis of enantioenriched triflouromethylated indolin-2-ones bearing adjacent tertiary chiral centers in good yields and good to excellent diastereo- and… read more here.
Keywords: addition; ones trifluoroethylidene; squaramide catalyst; pyrazol ones ... See more keywords
Ru(II)-catalyzed regioselective [4 + 1] redox-neutral spirocyclization of aryl amidines with diazopyrazolones: direct access to spiro[indole-3,4'-pyrazol]-5'-ones
Sign Up to like & getrecommendations! Published in 2024 at "Organic Chemistry Frontiers"
DOI: 10.1039/d3qo02071a
Abstract: An efficient protocol to construct spiro[indole-3,4'-pyrazol]-5'-ones via ruthenium(II)-catalyzed selective C-H bond activation/[4 + 1] spirocyclization starting from easily available N-aryl amidines and diazopyrazolones has been developed. A series of spiro-pyrazolones... read more here.
Keywords: indole pyrazol; amidines diazopyrazolones; spiro indole; aryl amidines ... See more keywords