Synthesis and antioxidant activity of some new N-alkylated pyrazole-containing benzimidazoles
Sign Up to like & getrecommendations! Published in 2017 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/s10593-017-2036-6
Abstract: A series of new N-substituted pyrazole-containing benzimidazoles was synthesized starting from 1,2-diaminobenzene and pyrazole-4-carbaldehyde in good yield. Antioxidant activity of all title compounds was assessed using 2,2-diphenyl-1-picrylhydrazyl and hydrogen peroxide assays. Some of the synthesized… read more here.
Keywords: antioxidant activity; activity new; containing benzimidazoles; synthesis antioxidant ... See more keywords
Intramolecular Azo Coupling Reaction of Binaphthyl Compounds: Synthesis of Pyrazole-Containing Helicene-Like Molecules.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c00974
Abstract: A method for accessing pyrazole-containing helicene-like molecules from easily accessible NOBIN derivatives was developed. The reaction proceeded efficiently via diazonium salt intermediates, which provided a series of helicene-like molecular products in yields of 77%-89% regardless… read more here.
Keywords: containing helicene; reaction; helicene like; helicene ... See more keywords
Synthesis, evaluation, molecular dynamics simulation and targets identification of novel pyrazole-containing imide derivatives
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2020.1745284
Abstract: Abstract A new series of novel pyrazole-containing imide derivatives were synthesized and evaluated for their anticancer activities against A-549, Bel7402, and HCT-8 cell lines. Among these compounds A2, A4, A11 and A14 possessed high inhibition… read more here.
Keywords: molecular dynamics; pyrazole containing; containing imide; imide derivatives ... See more keywords