Articles with "pyrazole triazole" as a keyword



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An advanced primary explosive and secondary explosive based on a zwitterionic pyrazole-triazole derivative.

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Published in 2022 at "Chemical communications"

DOI: 10.1039/d2cc04531a

Abstract: Two zwitterionic energetic materials containing a pyrazole-triazole backbone were synthesized and fully characterized. Compound 3 can serve as an ideal secondary explosive due to its high decomposition temperature (>200 °C), low impact sensitivity (>40 J),… read more here.

Keywords: secondary explosive; primary explosive; pyrazole triazole; advanced primary ... See more keywords
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Pyrazole and Triazole Derivatives as Mycobacterium tuberculosis UDP-Galactopyranose Inhibitors

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Published in 2022 at "Pharmaceuticals"

DOI: 10.3390/ph15020197

Abstract: UDP-galactopyranose mutase (UGM) is an essential enzyme involved in the bacterial cell wall synthesis, and is not present in mammalian cells. Thus, UGM from Mycobacterium tuberculosis (Mtb) represents a novel and attractive drug target for… read more here.

Keywords: mycobacterium tuberculosis; tuberculosis; derivatives mycobacterium; triazole derivatives ... See more keywords