Catalytic and Multicomponent Reactions for Green Synthesis of Some Pyrazolone Compounds and Evaluation as Antimicrobial Agents
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DOI: 10.1021/acsomega.2c03070
Abstract: A green synthetic approach and facile method was developed to produce pyrazole compounds (6a–d) by the reaction of ethyl acetoacetate (1), hydrazines (2a–d), and catalytic imidazole (3) in aqueous media. 4-Dicyanomethylene-2-pyrazoline-5-one derivatives (14a–d) were synthesized… read more here.
Keywords: catalytic multicomponent; pyrazoline one; multicomponent reactions; reactions green ... See more keywords