Catalytic asymmetric [4 + 1] cycloaddition to synthesize chiral pyrazoline-spirooxindoles
Sign Up to like & getrecommendations! Published in 2023 at "Organic Chemistry Frontiers"
DOI: 10.1039/d3qo00320e
Abstract: An asymmetric formal [4 + 1] cycloaddition of N-unprotected oxindole 3-pyridinium salts and α-halo hydrazones to access chiral pyrazoline-spirooxindoles is realized by using a chiral N,N’-dioxide-Pr(OTf)3 complex as catalyst. The... read more here.
Keywords: asymmetric cycloaddition; catalytic asymmetric; pyrazoline spirooxindoles; chiral pyrazoline ... See more keywords