Novel Pyrazoline and Pyrazoline–Thiazole Derivatives Linked to Tetrahydronaphthalene Ring: Synthesis, Anticancer Evaluation, VEGFR ‐2 Inhibition Activity, and Molecular Docking Study
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Heterocyclic Chemistry"
DOI: 10.1002/jhet.70123
Abstract: A new series of pyrazoline and pyrazoline–thiazole derivatives conjugated with tetralin ring 5a, b–19 was created starting with the chalcones 3a , b . The new compounds were tested as potential anticancer agents on three… read more here.
Keywords: molecular docking; pyrazoline thiazole; pyrazoline pyrazoline; thiazole derivatives ... See more keywords
New naphthalene-linked pyrazoline–thiazole hybrids as prominent antilung and antibreast cancer inhibitors
Sign Up to like & getrecommendations! Published in 2024 at "Turkish Journal of Chemistry"
DOI: 10.55730/1300-0527.3704
Abstract: The epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), pioneer members of the receptor tyrosine kinase subfamily, are frequently mutated and/or overexpressed in several types of human cancers, including nonsmall… read more here.
Keywords: cancer; pyrazoline thiazole; linked pyrazoline; thiazole hybrids ... See more keywords