Lipase mediated multicomponent synthesis of 1H-Pyrazolo[1,2-b]phthalazine-5,10-dione derivatives in binary solvent medium.
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology and applied biochemistry"
DOI: 10.1002/bab.2264
Abstract: A new method for the synthesis of 1H-Pyrazolo[1,2-b]phthalazine-5,10-dione derivatives via lipase from Aspergillus niger (ANL) catalyzed multicomponent reaction of aldehydes, malononitrile, and phthalhydrazide is reported herein for the first time. This novel method holds several… read more here.
Keywords: phthalazine dione; synthesis pyrazolo; lipase; dione derivatives ... See more keywords
β-Cyclodextrin as a Supramolecular Catalyst for the Synthesis of 1H-Pyrazolo[1,2-b]phthalazine-5,10-dione Derivatives in Water
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DOI: 10.1007/s10562-017-2032-6
Abstract: An efficient and green method has been developed for the synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones derivatives by employing 20 mol% β-cyclodextrin via a one-pot multicomponent reaction of aldehydes, malononitrile and phthalhydrazide in H2O–EtOH (4:1) at 100 °C for first… read more here.
Keywords: pyrazolo phthalazine; catalyst; synthesis pyrazolo;
Synthesis of novel spiro[chromeno[4′,3′:3,4]pyrazolo[1,2-b]phthalazine-7,3′-indoline]-2′,6,9,14-tetraone
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the Iranian Chemical Society"
DOI: 10.1007/s13738-018-1506-9
Abstract: Fe3O4@Cys–SO3H magnetic nanocatalyst has been used as an effective and reusable solid acid catalyst for the one pot synthesis of novel spiro[chromeno[4′,3′:3,4]pyrazolo[1,2-b]phthalazine-7,3′-indoline]-2′,6,9,14-tetraone via a three-component reaction of phthalhydrazide, 4-hydroxycoumarin and isatin derivatives. Easy separation of… read more here.
Keywords: novel spiro; synthesis novel; chromeno pyrazolo; spiro chromeno ... See more keywords
Cholinesterases, α-glycosidase, and carbonic anhydrase inhibition properties of 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives: Synthetic analogues for the treatment of Alzheimer's disease and diabetes mellitus.
Sign Up to like & getrecommendations! Published in 2020 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2020.103647
Abstract: In this study, using the Cu(OTf)2 catalyst, 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivative molecules were carried out in one step and with high yield (86-91%). The previously synthesized 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives, carbonic anhydrase I and II isozymes (hCA I and… read more here.
Keywords: phthalazine dione; pyrazolo phthalazine; carbonic anhydrase; dione derivatives ... See more keywords
Experimental and DFT mechanistic insights into one-pot synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones under catalysis of DBU-based ionic liquids
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DOI: 10.1039/d0nj03478a
Abstract: Benzylation of DBU followed by anion exchange of the resulting salt with trifluoroacetate gave nearly quantitatively the ionic liquid [Bn-DBU][TFA]. It is shown here to be an efficient catalyst for the synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones via… read more here.
Keywords: ionic liquid; phthalazine diones; synthesis pyrazolo; dbu ... See more keywords
NiFe2O4@B,N,F-tridoped CeO2 (NFTDNC): a mesoporous nanocatalyst in the synthesis of pyrazolopyranopyrimidine and 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives and as an adsorbent.
Sign Up to like & getrecommendations! Published in 2022 at "Dalton transactions"
DOI: 10.1039/d2dt01216b
Abstract: Mesoporous materials, due to their unique textural and structural features and successful applications in different scientific areas, engrossed our curiosity to form a mesoporous nanostructure. A facile method for the formation of nickel ferrite immobilized… read more here.
Keywords: nftdnc mesoporous; spectroscopy; microscopy; nanocatalyst ... See more keywords