Synthesis of some new pyrazolo[5,1-c][1,2,4]triazine derivatives and computational study
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DOI: 10.1016/j.molstruc.2020.128850
Abstract: Abstract In this study, the synthesis novel of seven new pyrazolo [5,1-c][1,2,4]triazin derivative disperse dyestuffs was reported. First, 2-arylhydrazone-3-ketiminobutyronitriles were synthesized and reacted with hydrazine hydrate to afford 5-amino-4-arylazo-3-methyl-1H-pyrazoles. The 5-amino-4-arylazo-3-methyl-1H-pyrazoles were diazotised and coupled… read more here.
Keywords: pyrazolo triazine; new pyrazolo; synthesis new; study synthesis ... See more keywords
Synthesis, Structural Characterization, and Biological Activity of New Pyrazolo[4,3-e][1,2,4]triazine Acyclonucleosides
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DOI: 10.3390/molecules25010221
Abstract: A series of new pyrazolo[4,3-e][1,2,4]triazine acyclonucleosides 2–5 and 8 were prepared and evaluated for their anticancer activity against human cancer cell lines (MCF-7, K-562) and CDK2/E, as well as Abl protein kinases inhibitors. Lipophilicity of… read more here.
Keywords: triazine acyclonucleosides; activity; pyrazolo triazine; new pyrazolo ... See more keywords