Discovery of Pyrazolopyridine Derivatives as HPK1 Inhibitors.
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DOI: 10.1021/acsmedchemlett.2c00238
Abstract: In spite of the great success of immune checkpoint inhibitors in immune-oncology therapy, an urgent need still exists to identify alternative approaches to broaden the scope of therapeutic coverage. Hematopoietic progenitor kinase 1 (HPK1), also… read more here.
Keywords: derivatives hpk1; discovery pyrazolopyridine; chemistry; pyrazolopyridine derivatives ... See more keywords