Novel pyrazolopyrimidine urea derivatives: Synthesis, antiproliferative activity, VEGFR‐2 inhibition, and effects on the cell cycle profile
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DOI: 10.1002/ardp.201900319
Abstract: A series of novel diaryl urea pyrazolopyrimidine derivatives was designed and synthesized. All the synthesized compounds were evaluated for cytotoxic activity by the National Cancer Institute. A significant antiproliferative activity at a 10‐µM dose was… read more here.
Keywords: cell cycle; pyrazolopyrimidine; antiproliferative activity; vegfr ... See more keywords