Synthesis and properties of 1-[(adamantan-1-yl)methyl]-3-pyrazolyl ureas
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DOI: 10.1007/s10593-019-02428-2
Abstract: A series of 1,3-disubstituted ureas containing 1,3,5-trisubstituted pyrazole and (adamantan-1-yl)methyl fragments were synthesized in the reaction of 1-(isocyanatomethyl)adamantane with 3- or 4-aminopyrazoles under mild conditions in 67-92% yields. The inhibitory activity of the obtained compounds… read more here.
Keywords: methyl; adamantan methyl; synthesis properties; pyrazolyl ureas ... See more keywords