De novo pyrimidine synthesis is necessary for intestinal colonization of Salmonella Typhimurium in chicks
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0183751
Abstract: pyrE (STM3733) encodes orotate phosphoribosyltransferase (OPRTase; EC 2.4.2.10), the fifth enzyme of the de novo pyrimidine biosynthetic pathway. We identified a ΔpyrE mutant as under selection in screening of a Salmonella mutant library in 4-day… read more here.
Keywords: synthesis necessary; pyre mutant; salmonella; colonization ... See more keywords