Articles with "pyridazine" as a keyword



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Six New Complexes Based on Substituted Pyridazine Ligands: Structures and Luminescent Properties

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Published in 2017 at "Journal of Chemical Crystallography"

DOI: 10.1007/s10870-017-0699-6

Abstract: AbstractThree structurally related ligands 3-chloro-6-(benzoimidazol-1-yl)pyridazine (L1), 3-chloro-6-(1,2,4-triazol-1-yl)pyridazine (L2) and 3,6-bis(imidazol-1-yl)pyridazine (L3) were designed and synthesized, and six new Zn(II), Co(II), Cu(II) and Cd(II) complexes, namely, [M(L1)2Cl2] [M = Zn (1) and Co (2)], [Cu(L2)2(NO3)2(H2O)] (3), [Cu(L2)2Cl2]∞ (4),… read more here.

Keywords: new complexes; topology; six new; complexes based ... See more keywords
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Design and synthesis of novel pyridazine N-aryl acetamides: In-vitro evaluation of α-glucosidase inhibition, docking, and kinetic studies.

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Published in 2020 at "Bioorganic chemistry"

DOI: 10.1016/j.bioorg.2020.104071

Abstract: We herein applied the four step-synthetic route to prepare the pyridazine core attached to the various N-aryl acetamides. By this approach, a new series of pyridazine-based compounds were synthesized, characterized and evaluated for their activities… read more here.

Keywords: aryl acetamides; kinetic studies; docking kinetic; pyridazine ... See more keywords
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Synthesis and structure-activity relationship study of novel 3-heteroarylcoumarins based on pyridazine scaffold as selective MAO-B inhibitors.

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Published in 2017 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2017.07.045

Abstract: Compounds of hybrid structure pyridazine-coumarin were discovered as potent, selective and reversible inhibitors of monoamine oxidase B (MAO-B). These compounds were synthesized in good yield following a multistep approach based on Knoevenagel reaction and using… read more here.

Keywords: mao; structure activity; synthesis structure; structure ... See more keywords
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Synthesis, crystal structure characterization, DFT calculations, Hirshfeld surface analysis and 3D energy frameworks of triazole pyridazine derivatives: Theoretical and experimental studies

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Published in 2021 at "Journal of Molecular Structure"

DOI: 10.1016/j.molstruc.2021.131242

Abstract: Abstract Recently, pyridazine derivatives have shown considerable biological properties such as anti-tumor and anti-inflammatory activity. The studied compounds 6-chloro-3-[(4-methylphenoxy)methyl][1,2,4] triazolo[4,3-b]pyridazine (8a) and 6-chloro-3-[(4-fluorophenoxy)methyl][1,2,4] triazolo[4,3-b]pyridazine (8b) have been synthesized and characterized by NMR, IR and mass… read more here.

Keywords: theoretical experimental; pyridazine; hirshfeld surface; pyridazine derivatives ... See more keywords
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Nitrogen-Rich Tetrazolo[1,5-b]pyridazine: Promising Building Block for Advanced Energetic Materials.

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Published in 2020 at "Journal of the American Chemical Society"

DOI: 10.1021/jacs.0c00161

Abstract: Two metal-free explosives: tetrazolo[1,5-b]pyridazine-containing molecules, [6-azido-8-nitrotetrazolo[1,5-b]pyridazine-7-amine (3at) and 8-nitrotetrazolo[1,5-b]pyridazine-6,7-diamine (6)] were obtained via straightforward two-step synthetic routes from commercially available reagents. Compound 3at displays excellent detonation performance (Dv = 8746 m s-1 and P =… read more here.

Keywords: rich tetrazolo; promising building; tetrazolo pyridazine; nitrogen rich ... See more keywords
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Syntheses, crystal structures and thermal properties of catena-poly[cadmium(II)-di-μ-bromido-μ-pyridazine-κ2 N 1:N 2] and catena-poly[cadmium(II)-di-μ-iodido-μ-pyridazine-κ2 N 1:N 2]

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Published in 2023 at "Acta Crystallographica Section E: Crystallographic Communications"

DOI: 10.1107/s2056989023002001

Abstract: In the crystal structures of the title compounds, the cadmium cations are octahedrally coordinated by four halide anions and two pyridazine ligands in a trans-CdX 4N2 (X = Br, I) arrangement and are linked into… read more here.

Keywords: poly cadmium; crystal structures; pyridazine; catena poly ... See more keywords

A One-Pot Approach to Novel Pyridazine C-Nucleosides

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Published in 2021 at "Molecules"

DOI: 10.3390/molecules26082341

Abstract: The synthesis of glycosides and modified nucleosides represents a wide research field in organic chemistry. The classical methodology is based on coupling reactions between a glycosyl donor and an acceptor. An alternative strategy for new… read more here.

Keywords: novel pyridazine; pyridazine nucleosides; one pot; pyridazine ... See more keywords
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Electrochemical Characterization and CO2 Reduction Reaction of a Family of Pyridazine-Bridged Dinuclear Mn(I) Carbonyl Complexes

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Published in 2023 at "Molecules"

DOI: 10.3390/molecules28031138

Abstract: Three recently synthesized neutral dinuclear carbonyl manganese complexes with the pyridazine bridging ligand, of general formula [Mn2(μ-ER)2(CO)6(μ-pydz)] (pydz = pyridazine; E = O or S; R = methyl or phenyl), have been investigated by cyclic… read more here.

Keywords: dinuclear carbonyl; co2 reduction; reduction reaction; pyridazine ... See more keywords