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Published in 2017 at "Journal of Chemical Crystallography"
DOI: 10.1007/s10870-017-0699-6
Abstract: AbstractThree structurally related ligands 3-chloro-6-(benzoimidazol-1-yl)pyridazine (L1), 3-chloro-6-(1,2,4-triazol-1-yl)pyridazine (L2) and 3,6-bis(imidazol-1-yl)pyridazine (L3) were designed and synthesized, and six new Zn(II), Co(II), Cu(II) and Cd(II) complexes, namely, [M(L1)2Cl2] [M = Zn (1) and Co (2)], [Cu(L2)2(NO3)2(H2O)] (3), [Cu(L2)2Cl2]∞ (4),…
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Keywords:
new complexes;
topology;
six new;
complexes based ... See more keywords
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Published in 2020 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2020.104071
Abstract: We herein applied the four step-synthetic route to prepare the pyridazine core attached to the various N-aryl acetamides. By this approach, a new series of pyridazine-based compounds were synthesized, characterized and evaluated for their activities…
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Keywords:
aryl acetamides;
kinetic studies;
docking kinetic;
pyridazine ... See more keywords
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Published in 2017 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2017.07.045
Abstract: Compounds of hybrid structure pyridazine-coumarin were discovered as potent, selective and reversible inhibitors of monoamine oxidase B (MAO-B). These compounds were synthesized in good yield following a multistep approach based on Knoevenagel reaction and using…
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Keywords:
mao;
structure activity;
synthesis structure;
structure ... See more keywords
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Published in 2021 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2021.131242
Abstract: Abstract Recently, pyridazine derivatives have shown considerable biological properties such as anti-tumor and anti-inflammatory activity. The studied compounds 6-chloro-3-[(4-methylphenoxy)methyl][1,2,4] triazolo[4,3-b]pyridazine (8a) and 6-chloro-3-[(4-fluorophenoxy)methyl][1,2,4] triazolo[4,3-b]pyridazine (8b) have been synthesized and characterized by NMR, IR and mass…
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Keywords:
theoretical experimental;
pyridazine;
hirshfeld surface;
pyridazine derivatives ... See more keywords
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Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.0c00161
Abstract: Two metal-free explosives: tetrazolo[1,5-b]pyridazine-containing molecules, [6-azido-8-nitrotetrazolo[1,5-b]pyridazine-7-amine (3at) and 8-nitrotetrazolo[1,5-b]pyridazine-6,7-diamine (6)] were obtained via straightforward two-step synthetic routes from commercially available reagents. Compound 3at displays excellent detonation performance (Dv = 8746 m s-1 and P =…
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Keywords:
rich tetrazolo;
promising building;
tetrazolo pyridazine;
nitrogen rich ... See more keywords
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Published in 2023 at "Acta Crystallographica Section E: Crystallographic Communications"
DOI: 10.1107/s2056989023002001
Abstract: In the crystal structures of the title compounds, the cadmium cations are octahedrally coordinated by four halide anions and two pyridazine ligands in a trans-CdX 4N2 (X = Br, I) arrangement and are linked into…
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Keywords:
poly cadmium;
crystal structures;
pyridazine;
catena poly ... See more keywords
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Published in 2021 at "Molecules"
DOI: 10.3390/molecules26082341
Abstract: The synthesis of glycosides and modified nucleosides represents a wide research field in organic chemistry. The classical methodology is based on coupling reactions between a glycosyl donor and an acceptor. An alternative strategy for new…
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Keywords:
novel pyridazine;
pyridazine nucleosides;
one pot;
pyridazine ... See more keywords
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Published in 2023 at "Molecules"
DOI: 10.3390/molecules28031138
Abstract: Three recently synthesized neutral dinuclear carbonyl manganese complexes with the pyridazine bridging ligand, of general formula [Mn2(μ-ER)2(CO)6(μ-pydz)] (pydz = pyridazine; E = O or S; R = methyl or phenyl), have been investigated by cyclic…
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Keywords:
dinuclear carbonyl;
co2 reduction;
reduction reaction;
pyridazine ... See more keywords