Articles with "pyridazinone synthon" as a keyword



2-Methyl-6-(4-aminophenyl)-4,5-dihydro-3(2H)-pyridazinone Synthon for Some New Annelated 1,2,3-Selena/Thiadiazoles and 2H-Diazaphospholes with Anticipated Biological Activity and Quantum Chemical Calculations

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Published in 2023 at "Molecules"

DOI: 10.3390/molecules28031280

Abstract: A convenient and efficient synthetic protocol for the new selenadiazole. Thiadiazole and diazaphosphole derivatives incorporating a pyridazine moiety originating from 4-(4-aminophenyl)-4-oxobutanoic acid (1) were described. All newly synthesized compounds were evaluated for their antimicrobial activity… read more here.

Keywords: pyridazinone synthon; dihydro pyridazinone; aminophenyl dihydro; biological activity ... See more keywords