Indolizine synthesis via radical cyclization and demethylation of sulfoxonium ylides and 2-(pyridin-2-yl)acetate derivatives
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DOI: 10.1039/d1qo00550b
Abstract: A novel radical cross-coupling/cyclization of 2-(pyridin-2-yl)acetate derivatives and sulfoxonium ylides is developed, which provides a straightforward access to structurally diverse methylthio-substituted indolizine. A series of 1,2,3-trisubstituted indolizines are readily synthesized in modest yields. In this… read more here.
Keywords: sulfoxonium ylides; sulfoxonium; cyclization; acetate derivatives ... See more keywords