Articles with "pyridin thiazolidin" as a keyword



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Novel 2-phenyl-3-(Pyridin-2-yl) thiazolidin-4-one derivatives as potent inhibitors for proliferation of osteosarcoma cells in vitro and in vivo.

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Published in 2021 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2021.114010

Abstract: Due to unknown pathogenesis and unidentified drug target, no drug for the treatment of osteosarcoma (OS) has been launched to the market. Herein, thiazolidinone 1a was discovered as a hit compound by phenotypic screening with… read more here.

Keywords: derivatives potent; one derivatives; phenyl pyridin; thiazolidin one ... See more keywords