Synthesis, Docking and Anticancer Evaluation of New Pyridine-3-Carbonitrile Derivatives
Sign Up to like & getrecommendations! Published in 2021 at "Polycyclic Aromatic Compounds"
DOI: 10.1080/10406638.2020.1870507
Abstract: N'-(2-((4-(Benzo[d][1, 3]dioxol-5-yl)-3-cyano-6-(naphthalen-2-yl)-pyridin-2-yl)oxy)- acetyl)benzohydrazide (6) and hydrazide derivatives (7–10) were synthesized via reaction of 3-cyano-pyridinaceto... read more here.
Keywords: anticancer evaluation; pyridine carbonitrile; docking anticancer; synthesis docking ... See more keywords
Crystal structure and Hirshfeld surface analysis of hexakis(μ-benzoato-κ2 O:O′)bis(pyridine-3-carbonitrile-κN 1)trizinc(II)
Sign Up to like & getrecommendations! Published in 2017 at "Acta Crystallographica Section E: Crystallographic Communications"
DOI: 10.1107/s2056989017016899
Abstract: The asymmetric unit of the title complex contains one half of the complex molecule, one and a half ZnII cations, three benzoate (Bnz) and one pyridine-3-carbonitrile (CPy) molecule; the Bnz anions act as bidentate ligands… read more here.
Keywords: pyridine carbonitrile; hirshfeld surface; pyridine; surface analysis ... See more keywords
X-ray mapping in heterocyclic design: 18. X-ray diffraction study of a series of derivatives of 3-cyanopyridine-2-one with annelated heptane and octane cycles
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DOI: 10.1134/s1063774517020249
Abstract: Seven new, previously unknown, bicyclic and tricyclic heterocycles based on derivatives of 3-cyanopyrid-2-ones are obtained: 2-oxo-2,5,6,7,8,9-hexahydro-1H-cyclohepta[b]pyridine-3-carbonitrile, C11H12N2O (1a); 2-[2-(4-chlorophenyl)-2-oxoethoxy]-6,7,8,9-tetrahydro-5Н-cyclohepta[b]pyridine-3-carbonitrile, C19H17ClN2O2 (2a); (3-amino-6,7,8,9-tetrahydro-5H-cyclohepta[b]furo[3,2-e]pyridin-2-yl)(4- chlorophenyl)methanone, C19H17ClN2O2 (3); 2-oxo-1,2,5,6,7,8,9,10-octahydrocycloocta[b]pyridine-3-carboxamide, C12H16N2O2 (4); 2-[2-(4-chorophenyl)-2-oxoethoxy]-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine-3-carboxamide, C20H21ClN2O3 (5a); 1-[2-(4-chlorophenyl)-2-oxoethyl]-2-oxo-1,2,5,6,7,8,9,10-octahydrocycloocta[b]pyridine-3-carboxamide, C20H21ClN2O3 (5b); and… read more here.
Keywords: chlorophenyl; pyridine carbonitrile; pyridine; ray diffraction ... See more keywords