2-Guanidyl pyridine PNA nucleobase for triple-helical Hoogsteen recognition of cytosine in double-stranded RNA.
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DOI: 10.1039/d2cc02615e
Abstract: In triplex-forming peptide nucleic acid, a novel 2-guanidyl pyridine nucleobase (V) enables recognition of up to two cytosine interruptions in polypurine tracts of dsRNA by engaging the entire Hoogsteen face of C-G base pair. Ab… read more here.
Keywords: recognition; cytosine; pyridine pna; pna nucleobase ... See more keywords