Design and Synthesis of 2,5-Disubstituted-1,3,4-Oxadiazole Hybrids Bearing Pyridine and 1,2,3-Triazole Pharmacophores
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DOI: 10.1002/jhet.2672
Abstract: A novel series of 2,5-disubstituted-1,3,4-oxadiazoles decorated with two biodynamic moieties pyridine and 1,2,3-triazole have been successfully synthesized in good yields under mild reaction conditions. The synthesized compounds are valuable for biological activity exploration since three… read more here.
Keywords: design synthesis; hybrids bearing; pyridine triazole; disubstituted oxadiazole ... See more keywords
Two groups of copperII pyridine–triazole complexes with “open or close” pepper rings and their in vitro antitumor activities
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DOI: 10.1039/c9ra10677d
Abstract: Based on 1,2-dimethoxyphenyl (veratrole, open) and 1,2-methylenedioxyphenyl (pepper ring, close)-derived pyridine–triazole analogues, two groups of copper(II) complexes, namely, Group I(C1–C3) and Group II(C4–C6) were synthesized and fully characterized. All ligands and complexes were tested in… read more here.
Keywords: triazole complexes; two groups; copperii pyridine; pyridine triazole ... See more keywords
Modified pyridine-triazole and 2,2'-bipyrimidine ligands generating robust titanium complexes constructed around a TiO4N2 core.
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DOI: 10.1039/d1dt03172d
Abstract: The synthesis and characterisation of novel chelate nitrogen ligands with phasmidic tails (pyridine-triazole ligand 1b; 2,2'-bipyrimidine ligands 2b and 3b) as well as their titanium(IV) coordination complexes are reported. The analogous ligands 1a, 2a and… read more here.
Keywords: pyridine triazole; titanium; titanium complexes; bipyrimidine ligands ... See more keywords