Synthesis, antitubercular evaluation, and molecular docking studies of hybrid pyridinium salts derived from isoniazid
Sign Up to like & getrecommendations! Published in 2023 at "Drug Development Research"
DOI: 10.1002/ddr.22039
Abstract: In the quest to develop potent inhibitors for Mycobacterium tuberculosis, novel isoniazid‐based pyridinium salts were designed, synthesized, and tested for their antimycobacterial activities against the H37Rv strain of Mycobacterium tuberculosis using rifampicin as a standard.… read more here.
Keywords: derived isoniazid; synthesis antitubercular; pyridinium salts; antitubercular evaluation ... See more keywords
Charge Transfer Complexes (CTCs) with Pyridinium Salts: Towards Efficient Dual Photochemical/Thermal Initiators and 3D Printing Applications.
Sign Up to like & getrecommendations! Published in 2022 at "Macromolecular rapid communications"
DOI: 10.1002/marc.202200314
Abstract: In both organic and polymer synthesis, photochemistry of Charge Transfer Complexes (CTCs) is considered as a powerful approach to expand visible-light-driven radical chemistry reaction. We report herein on the development of a class of useful… read more here.
Keywords: transfer complexes; pyridinium salts; complexes ctcs; charge transfer ... See more keywords
N-Substituted pyridinium salts as reagents for radical functionalization using visible light (microreview)
Sign Up to like & getrecommendations! Published in 2020 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/s10593-020-02788-0
Abstract: Novel visible light mediated methods for radical functionalization using N-substituted pyridinium salts are highlighted. This microreview summarizes literature data published over the last 5 years. read more here.
Keywords: functionalization using; visible light; radical functionalization; substituted pyridinium ... See more keywords
Simple and double pyridinium salts with cyanobiphenyl groups as ionic liquids and ionic liquid crystals: synthesis and investigation of thermal behavior
Sign Up to like & getrecommendations! Published in 2017 at "Research on Chemical Intermediates"
DOI: 10.1007/s11164-017-3212-0
Abstract: A series of mono- and di-cationic pyridinium salts with one or two promesogenic cyanobiphenyl groups and different counterions, bromide, dodecylsulfate or dioctyl sulfosuccinate, were designed and prepared while their thermal properties were investigated by means… read more here.
Keywords: ionic liquid; double pyridinium; pyridinium; simple double ... See more keywords
Synthesis, characterization of calix[5]azulene and its complexation with pyridinium salts
Sign Up to like & getrecommendations! Published in 2021 at "Tetrahedron"
DOI: 10.1016/j.tet.2021.132146
Abstract: Abstract Calix[5]azulene (CA5) was synthesized from bis(guaiazulene-3-yl)methane and azulene in the presence of sulfuric acid. Three crystal structures were collected from different solvent systems, of which the conformation of CA5 molecules resemble to each other.… read more here.
Keywords: pyridinium salts; complexation; calix azulene; synthesis characterization ... See more keywords
N-Functionalized Pyridinium Salts: A New Chapter for Site-Selective Pyridine C-H Functionalization via Radical-Based Processes under Visible Light Irradiation.
Sign Up to like & getrecommendations! Published in 2022 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.2c00530
Abstract: ConspectusThe radical-mediated C-H functionalization of pyridines has attracted considerable attention as a powerful tool in synthetic chemistry for the direct functionalization of the C-H bonds of the pyridine scaffold. Classically, the synthetic methods for functionalized… read more here.
Keywords: functionalization; chemistry; pyridinium salts; visible light ... See more keywords
1,2-Dicarbofunctionalization of Trifluoromethyl Alkenes with Pyridinium Salts via a Cycloaddition/Visible-Light-Enabled Fragmentation Cascade.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.1c04148
Abstract: Although trifluoromethyl alkenes have great synthetic potential, their 1,2-difunctionalization has been a challenge. In this Letter, we disclose the first 1,2-dicarbofunctionalization of trifluoromethyl alkenes with pyridinium salts via a cascade process involving a base-promoted [3… read more here.
Keywords: salts via; dicarbofunctionalization trifluoromethyl; pyridinium salts; visible light ... See more keywords
Aggregation phenomena in photobicyclised pyridinium salts
Sign Up to like & getrecommendations! Published in 2017 at "New Journal of Chemistry"
DOI: 10.1039/c7nj02788e
Abstract: The possible formation of aggregates in a solution of two planar heterocyclic salts, 2-phenylbenzo[8,9]quinolizino[4,5,6,7-fed]phenanthridinylium tetrafluoroborate (PQPBF4) and thienyl-substituted 2-phenylbenzo[ij]pyrido[2,1,6-de]dithieno[3,2-b:2′,3′-g]quinolizin-13-ium perchlorate (BPDTQClO4), was investigated in organic solvents and in water, by the analysis of their UV-Vis… read more here.
Keywords: aggregation phenomena; phenomena photobicyclised; photobicyclised pyridinium; water ... See more keywords
Catalytic enantioselective synthesis of 1,4-dihydropyridines via the addition of C(1)-ammonium enolates to pyridinium salts
Sign Up to like & getrecommendations! Published in 2021 at "Chemical Science"
DOI: 10.1039/d1sc03860e
Abstract: The regio- and stereoselective addition of C(1)-ammonium enolates – generated in situ from aryl esters and the isothiourea catalyst (R)-BTM – to pyridinium salts bearing an electron withdrawing substituent in the 3-position allows the synthesis… read more here.
Keywords: pyridinium salts; ammonium enolates; addition; addition ammonium ... See more keywords
Skeletal remodeling of chalcone-based pyridinium salts to access isoindoline polycycles and their bridged derivatives
Sign Up to like & getrecommendations! Published in 2021 at "Chemical Science"
DOI: 10.1039/d1sc05741c
Abstract: Simultaneous deconstructive ring-opening and skeletal reconstruction of an inert, aromatic pyridinium ring is of great importance in synthetic communities. However, research in this area is still in its infancy. Here, a skeletal re-modeling strategy was… read more here.
Keywords: isoindoline polycycles; pyridinium salts; pyridinium; based pyridinium ... See more keywords
Bromide-mediated, C2-selective, and oxygenative alkylation of pyridinium salts using alkenes and molecular oxygen.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical communications"
DOI: 10.1039/d2cc06138d
Abstract: Herein, we report a bromide-mediated, C2-selective, and oxygenative alkylation of pyridinium salts using alkenes and O2 for the synthesis of important β-2-pyridyl ketones. Notably, a quaternary carbon center was successfully installed at the C2-position of… read more here.
Keywords: oxygenative alkylation; alkylation pyridinium; mediated selective; bromide mediated ... See more keywords