Indolyl-Pyridinyl-Propenone-Induced Methuosis through the Inhibition of PIKFYVE
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DOI: 10.1021/acsomega.8b00202
Abstract: Methuosis is a form of nonapoptotic cell death characterized by the accumulation of macropinosome-derived vacuoles. Herein, we identify PIKFYVE, a class III phosphoinositide (PI) kinase, as the protein target responsible for the methuosis-inducing activity of… read more here.
Keywords: pikfyve; propenone induced; indolyl pyridinyl; methuosis ... See more keywords
Synthesis and Fungicidal Activity of Substituted N-(Alkoxy)-1-(3-pyridinyl)methanonimines
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DOI: 10.1134/s1070363219110045
Abstract: A number of new substituted N-(alkoxy)-1-phenyl- and N-(alkoxy)-1-cyclohexyl-1-(3-pyridinyl)-methanonymines were prepared by reacting the corresponding N-hydroxyl derivatives with benzyl chloride under phase transfer catalysis in a 10% NaOH-benzene system, as well as with 1-bromohexane and bromocyclohexane… read more here.
Keywords: fungicidal activity; synthesis fungicidal; pyridinyl; substituted alkoxy ... See more keywords