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Published in 2017 at "Chemical research in toxicology"
DOI: 10.1021/acs.chemrestox.6b00394
Abstract: 2-Amino-9H-pyrido[2,3-b]indole (AαC) is the most abundant carcinogenic heterocyclic aromatic amine (HAA) formed in mainstream tobacco smoke. AαC is a liver carcinogen in rodents, but its carcinogenic potential in humans is not known. To obtain a…
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Keywords:
amino pyrido;
pyrido indol;
gluc;
pyrido indole ... See more keywords
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Published in 2023 at "Journal of Enzyme Inhibition and Medicinal Chemistry"
DOI: 10.1080/14756366.2023.2218602
Abstract: Abstract A new series of indole-2-carboxamides 5a-g, 6a-f and pyrido[3,4-b]indol-1-ones 7a and 7b have been developed as new antiproliferative agents that target both wild and mutant type EGFR. The antiproliferative effect of the new compounds…
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Keywords:
design synthesis;
egfrwt egfrt790m;
indole carboxamides;
carboxamides pyrido ... See more keywords
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Published in 2017 at "Molecular Crystals and Liquid Crystals"
DOI: 10.1080/15421406.2017.1338073
Abstract: ABSTRACT Four novel meta-linked carboline derivatives, two δ-carboline-based, 1, 3-bis (5H-pyrido[3,2-b]- indol-5-yl)benzene (mCdP) and 2,6-bis(5H-pyrido[3,2-b]indol-5-yl)pyridine (26mCdPy) were synthesized, as well as two α-carboline derivatives, 1,3-bis(9H-pyrido[2,3-b]indol-9-yl) benzene (mCaP) and 2,6-bis(9H-pyrido[2,3-b]indol-9-yl)pyridine (26mCaPy) as comparison. The triplet energy…
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Keywords:
bis pyrido;
carboline derivatives;
properties carboline;
pyrido indol ... See more keywords