Iodine-Mediated C═C Double Bond Cleavage toward Pyrido[2,1-b]quinazolinones.
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DOI: 10.1021/acs.orglett.2c01183
Abstract: A transition-metal-free C═C double bond cleavage reaction employing molecular iodine is described. In the presence of K2CO3 as the base, I2-mediated C═C bond cleavage followed by intramolecular annulation of N-(2-vinylaryl)pyridin-2-amine substrates produces pyrido[2,1-b]quinazolinones and related… read more here.
Keywords: double bond; bond cleavage; pyrido quinazolinones; iodine mediated ... See more keywords