A solvent-free and efficient synthesis of bicyclic 2-pyridone derivatives for endoplasmic reticulum imaging
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DOI: 10.1039/d1qo00350j
Abstract: Starting from citric acid (CA) and ethylenediamine derivatives, a solvent-free, catalyst-free and high yielding synthesis approach for bicyclic 2-pyridones is presented. By continuously modifying the core structure, a series of novel and bright fluorophores with… read more here.
Keywords: endoplasmic reticulum; synthesis; solvent free; pyridone derivatives ... See more keywords
Design, Synthesis and Characterization of 2-pyridone Derivatives as C-Jun N-terminal Kinases (JNKs) Signaling Pathway Inhibitors
Sign Up to like & getrecommendations! Published in 2017 at "Research Journal of Pharmacy and Technology"
DOI: 10.5958/0974-360x.2017.00684.9
Abstract: A new series of 2-pyridone derivatives (A1-A6) were synthesized by various substitution and their structures were confirmed by spectral and elemental analyses. The cytotoxic activities of the newly synthesized compounds were docked against JNKs (2WAJ… read more here.
Keywords: pyridone derivatives; jun terminal; kinases jnks; terminal kinases ... See more keywords