A Synthetic Methodology Toward Pyrrolo[2,3- b]pyridones for GC Base Pair Recognition.
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DOI: 10.1021/acs.orglett.8b03111
Abstract: Flexible synthetic access to a novel biarylic GC binding motif is presented, consisting of a pyridone connected to a fused pyrrolo[2,3- b]pyridone. Extensive molecular modeling led to an optimized design with perfect complementarity to the… read more here.
Keywords: pyrrolo pyridones; methodology; toward pyrrolo; synthetic methodology ... See more keywords