Exploring the therapeutic potential of Cu(II)-complexes with ligands derived from pyridoxal
Sign Up to like & getrecommendations! Published in 2020 at "Inorganica Chimica Acta"
DOI: 10.1016/j.ica.2020.119558
Abstract: Abstract Three new copper(II) complexes formulated as [Cu(L)(X)], where X = H2O or Cl and H2L is a Schiff base (H2L1,2) or its reduced version (H3L3Cl) derived from pyridoxal, are prepared, as well as two ternary complexes… read more here.
Keywords: derived pyridoxal; potential complexes; pyridoxal; therapeutic potential ... See more keywords
Structural attributes and substrate specificity of pyridoxal kinase from Leishmania donovani.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2020.02.257
Abstract: The enzyme pyridoxal kinase (PdxK) catalyzes the conversion of pyridoxal to pyridoxal-5'-phosphate using ATP as the co-factor. The product pyridoxal-5'-phosphate (PLP) plays a key role in several biological processes such as transamination, decarboxylation and deamination.… read more here.
Keywords: leishmania donovani; pyridoxal kinase; pyridoxal; ldpdxk ... See more keywords
Nature-Inspired Radical Pyridoxal-Mediated C-C Bond Formation.
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DOI: 10.1021/jacs.4c05997
Abstract: Pyridoxal-5'-phosphate (PLP) and derivatives of this cofactor enable a plethora of reactions in both enzyme-mediated and free-in-solution transformations. With few exceptions in each category, such chemistry has predominantly involved two-electron processes. This sometimes poses a… read more here.
Keywords: pyridoxal; inspired radical; nature inspired; radical pyridoxal ... See more keywords