Ca2+ functions as a molecular switch that controls the mutually exclusive complex formation of pyridoxal phosphatase with CIB1 or calmodulin
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DOI: 10.1002/1873-3468.13795
Abstract: Pyridoxal 5′‐phosphate (PLP) is an essential cofactor for neurotransmitter metabolism. Pyridoxal phosphatase (PDXP) deficiency in mice increases PLP and γ‐aminobutyric acid levels in the brain, yet how PDXP is regulated is unclear. Here, we identify… read more here.
Keywords: phosphatase; mutually exclusive; pdxp; pyridoxal phosphatase ... See more keywords