Synthesis, characterization and biological evaluation of tertiary sulfonamide derivatives of pyridyl-indole based heteroaryl chalcone as potential carbonic anhydrase IX inhibitors and anticancer agents.
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DOI: 10.1016/j.ejmech.2018.05.034
Abstract: In the quest for novel effective carbonic anhydrase inhibitors, some sulfonamide derivatives of pyridyl-indole based chalcone were synthesized and screened in vitro for inhibitory activity against human carbonic anhydrase IX isoform. Among all the synthesized compounds… read more here.
Keywords: anhydrase inhibitors; carbonic anhydrase; sulfonamide derivatives; pyridyl indole ... See more keywords