Synthesis, Biological Activity, and Mechanism of Action of 2‐Pyrazyl and Pyridylhydrazone Derivatives, New Classes of Antileishmanial Agents
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DOI: 10.1002/cmdc.201800328
Abstract: In this work, we report the antileishmanial activity of 23 compounds based on 2‐pyrazyl and 2‐pyridylhydrazone derivatives. The compounds were tested against the promastigotes of Leishmania amazonensis and L. braziliensis, murine macrophages, and intracellular L. amazonensis amastigotes.… read more here.
Keywords: pyridylhydrazone derivatives; amazonensis; pyrazyl pyridylhydrazone; mechanism action ... See more keywords