Origins and spread of novel genetic variants of sulfadoxine–pyrimethamine resistance in Plasmodium falciparum isolates in Indonesia
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DOI: 10.1186/s12936-018-2597-6
Abstract: BackgroundWhile malaria incidence in Indonesia has decreased threefold in the last decade, more than 200,000 cases were reported in 2016. Different endemicity of Plasmodium falciparum malaria among several islands in Indonesia has been recognized and… read more here.
Keywords: pfdhps; plasmodium falciparum; resistance; sulfadoxine pyrimethamine ... See more keywords
Development and Evaluation of a Novel HNB Based Isothermal Amplification Assay for Fast Detection of Pyrimethamine Resistance (S108N) in Plasmodium falciparum
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DOI: 10.3390/ijerph16091635
Abstract: Sulphadoxine and pyrimethamine (SP) have been used as long-acting partner antimalarial drugs in artemisinin combination therapy (ACT) for falciparum malaria. The emergence and increasing spread of SP resistance in malaria-endemic areas have become a challenge… read more here.
Keywords: detection pyrimethamine; falciparum; isothermal amplification; resistance ... See more keywords