Synthesis and Biological Evaluation of B-Cell Lymphoma 6 Inhibitors of N-phenyl-4-pyrimidinamine Derivatives Bearing Potent Activities against Tumor Growth.
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DOI: 10.1021/acs.jmedchem.9b01618
Abstract: The transcriptional repressor B-cell lymphoma 6 (BCL6) is frequently misregulated in diffuse large B-cell lymphoma (DLBCL) and has emerged as an attractive drug target for the treatments of lymphoma. In this article, a series of… read more here.
Keywords: potent activities; phenyl pyrimidinamine; pyrimidinamine derivatives; cell ... See more keywords