A comprehensive review on pyrimidine analogs-versatile scaffold with medicinal and biological potential
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2021.131168
Abstract: Abstract Pyrimidines are nitrogen-containing heterocycles known for anticancer, anti-HIV, antifungal, and antibacterial activities. Pyrimidines, compounds bearing this heterocycle, are common in many medicinal drugs. Based on these findings, we have also reported the synthesis and… read more here.
Keywords: versatile scaffold; pyrimidine analogs; comprehensive review; review pyrimidine ... See more keywords
Pyrimidine analogs as a new class of Gram-positive antibiotics, mainly targeting thymineless-death related proteins.
Sign Up to like & getrecommendations! Published in 2019 at "ACS infectious diseases"
DOI: 10.1021/acsinfecdis.9b00305
Abstract: Multidrug-resistant (MDR) bacteria are widespread throughout the world and pose an increasingly serious threat to human and animal health. Besides implementing strict measures to prevent improper antibiotic use, it remains essential that novel antibiotics must… read more here.
Keywords: gram positive; death; pyrimidine analogs; thymineless death ... See more keywords