Thieno[2,3‐d]pyrimidine‐Core Compounds Show Activity against Clinically Relevant Gram‐Positive Bacteria
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DOI: 10.1002/cmdc.202200207
Abstract: Thieno[2,3‐d]pyrimidines represent a novel antibacterial prodrug scaffold, previously identified through a screening campaign against Mycobacterium tuberculosis in which the formation of highly antimycobacterial metabolites catalyzed by the nitroreductase Mrx2 is suggested to be the relevant… read more here.
Keywords: thieno pyrimidine; pyrimidine core; activity; core compounds ... See more keywords