Design and Optimization of Novel Pyrimidine-Morpholine Hybrids Through Computational Approaches for SRC Kinase Inhibitory Activity
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DOI: 10.1055/a-2554-1119
Abstract: Abstract Src (non receptor tyrosine kinase) plays a role in multiple pathways leading to tumor survival, proliferation and metastasis. Inhibiting Src kinase would be a therapeutic benefit in Src dependent cancers. Most of the nitrogen… read more here.
Keywords: src kinase; morpholine hybrids; novel pyrimidine; pyrimidine morpholine ... See more keywords