Catalyst-Free Three-Component Tandem Green Synthesis of Pyrano[2,3-d]Pyrimidine Scaffolds in Ethylene Glycol (E-G) as a Recyclable Reaction Medium
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DOI: 10.1080/10406638.2020.1852582
Abstract: A green, efficient and convenient synthesis of pyrano[2,3-d]pyrimidine scaffolds has been developed via one-pot three-component reaction of aryl aldehyde derivatives, malononitrile with barbituric ... read more here.
Keywords: pyrano pyrimidine; three component; synthesis pyrano; pyrimidine scaffolds ... See more keywords
Functionalization of 2-Amino-3-benzyl-6-(benzylthio)pyrimidin-4(3H)-one: An Efficient Access to the Synthesis of Polycyclic Pyrimidine Scaffolds
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DOI: 10.1134/s107036322003024x
Abstract: 2-Aminouracil is used in the synthesis of a new series of tri- and tetracyclic pyrimidine scaffolds as the precursor. Thiazolo[5,4-d]triazolo[4,3-a]pyrimidine has been synthesized by diazotization and heterocyclization of the aminopyrimidinone derivative with nitrous acid at… read more here.
Keywords: synthesis; pyrimidine scaffolds; amino benzyl; benzyl benzylthio ... See more keywords
Therapeutic potential of heterocyclic pyrimidine scaffolds
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DOI: 10.1186/s13065-018-0406-5
Abstract: Heterocyclic compounds offer a high degree of structural diversity and have proven to be broadly and economically useful as therapeutic agents. Comprehensive research on diverse therapeutic potentials of heterocycles compounds has confirmed their immense significance… read more here.
Keywords: chemistry; potential heterocyclic; pyrimidine scaffolds; heterocyclic pyrimidine ... See more keywords