Synthesis and Antitumor Evaluation of Menthone-Derived Pyrimidine-Urea Compounds as Potential PI3K/Akt/mTOR Signaling Pathway Inhibitor
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DOI: 10.3389/fchem.2021.815531
Abstract: A series of novel menthone derivatives bearing pyrimidine and urea moieties was designed and synthesized to explore more potent natural product-derived antitumor agents. The structures of the target compounds were confirmed by FTIR, NMR, and… read more here.
Keywords: pyrimidine urea; pi3k akt; signaling pathway; menthone ... See more keywords