Identification of a pyrimidinetrione derivative as the potent DprE1 inhibitor by structure-based virtual ligand screening.
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DOI: 10.1016/j.bioorg.2018.12.018
Abstract: Despite the increasing need of new antituberculosis drugs, the number of agents approved for the market has fallen to an all-time low. In response to the emerging drug resistance followed, structurally unique chemical entities will… read more here.
Keywords: pyrimidinetrione derivative; identification pyrimidinetrione; dpre1; potent dpre1 ... See more keywords