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Published in 2022 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2022.114399
Abstract: Searching for new small molecules as photosensitizing agents, we have developed a class of twenty-five pyrimido[5,4-g]indolizine and pyrimido[4,5-c]pyrrolo[1,2-a]azepines with a good substitution pattern defining a versatile synthetic pathway to approach the title ring system. All…
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Keywords:
pyrimido;
pyrimido pyrrolo;
cancer;
indolizine pyrimido ... See more keywords
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1
Published in 2017 at "Tetrahedron"
DOI: 10.1016/j.tet.2017.03.082
Abstract: Abstract A rapid, efficient and benign protocol has been developed for the construction of potentially biologically active furo[2′,3′:4,5]pyrimido[2,1- b ][1,3]benzothiazole derivatives as major products along with (3 E )-3-[(alkylamino)methylene]-2 H -pyrimido[2,1- b ][1,3]benzothiazole-2,4(3 H )-dione…
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Keywords:
pyrimido;
pyrimido benzothiazole;
reaction;
one pot ... See more keywords
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0
Published in 2019 at "Tetrahedron"
DOI: 10.1016/j.tet.2019.01.009
Abstract: Abstract We have developed a straightforward approach to diverse synthesis of 2,3-, 2,4-disubstituted pyrimido [1,2-a]benzimidazoles, 2,4,10-trisubstituted 2,10-dihydropyrimido [1,2-a]benzimidazoles and 2,3-disubstituted imidazo [2,1-b]benzothiazoles via multicomponent reactions (MCRs) of heterocyclic azoles, aldehydes with easily storable and handling…
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Keywords:
pyrimido;
benzothiazoles via;
diverse synthesis;
imidazo benzothiazoles ... See more keywords
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2
Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c05896
Abstract: DABCO was used as a basic and inexpensive catalyst for the synthesis of some new benzyloxy pyrimido[4,5-b]quinoline derivatives and 1,2,3- triazole-fused pyrimido[4,5-b]quinolines by the one-pot multi-component reaction of various benzyloxy benzaldehydes or benzylic −1,2,3-triazol-4-yl-methoxy benzaldehydes…
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Keywords:
pyrimido quinolines;
synthesis novel;
catalyst synthesis;
pyrimido ... See more keywords
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0
Published in 2018 at "Acta crystallographica. Section C, Structural chemistry"
DOI: 10.1107/s2053229618002176
Abstract: A concise, efficient and versatile synthesis of amino-substituted benzo[b]pyrimido[5,4-f]azepines is described: starting from a 5-allyl-4,6-dichloropyrimidine, the synthesis involves base-catalysed aminolysis followed by intramolecular Friedel-Crafts cyclization. Four new amino-substituted benzo[b]pyrimido[5,4-f]azepines are reported, and all the products…
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Keywords:
pyrimido;
benzo pyrimido;
substituted benzo;
amino substituted ... See more keywords
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Published in 2017 at "Bulletin of the Chemical Society of Japan"
DOI: 10.1246/bcsj.20160250
Abstract: In the present work, electrochemical synthesis of novel pyrimido[4,5-b]indoles was directly carried out via the electrochemical oxidation of catechols in the presence of 2,4-diamino-6-hydroxypyrimidine in an aqueous media. The results suggested that electrogenerated o-benzoquinone moieties…
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Keywords:
pyrimido;
practical one;
one pot;
pot electrochemical ... See more keywords
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1
Published in 2017 at "Journal of Chemical Research"
DOI: 10.3184/174751917x15132496997778
Abstract: Several derivatives of the novel heterocyclic systems 2-substituted-imidazo- and benzimidazo-[2,1-b]pyrimido[4,5-d][1,3]thiazine have been synthesised through the one-pot cyclocondensation of 2,4-dichloro-5-(chloromethyl)-6-methylpyrimidine with imidazolidine-2-thione and 1H-benzimidazole-2(3H)-thione and subsequently substituted by various secondary amines in moderately good yields.
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Keywords:
synthesis novel;
pyrimido;
derivatives benz;
pyrimido thiazine ... See more keywords