Pyrimido[5,4-d]pyrimidine-Based Compounds as a Novel Class of Antitrypanosomal and Antileishmanial Agents.
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DOI: 10.1021/acsmedchemlett.2c00170
Abstract: Sleeping sickness and leishmaniasis are neglected tropical diseases that threaten millions of people. The currently available therapies present several limitations, including high toxicity, lack of efficacy, and emerging drug resistance, prompting a search for novel… read more here.
Keywords: antitrypanosomal antileishmanial; antileishmanial agents; pyrimido pyrimidine; novel class ... See more keywords