Synthesis and Antiproliferative Evaluation of New Pyrimido[1,6-a]Thieno[2,3-d]Pyrimidine Derivatives
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DOI: 10.1002/jhet.2592
Abstract: A facile one-pot synthesis of new pyrimido[1,6-a]thieno[2,3-d]pyrimidin-4-ones , is reported via base-catalyzed reaction of 2-amino-3-cyanothiophenes , with 2,4-dichloro-5-bromo-6-methylpyrimidine . Subsequent treatment of the products with several amines under a mild condition gave a host of… read more here.
Keywords: new pyrimido; cell; pyrimido thieno; synthesis antiproliferative ... See more keywords