Asymmetric autocatalysis of pyrimidyl alkanol and related compounds. Self-replication, amplification of chirality and implication for the origin of biological enantioenriched chirality
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DOI: 10.1016/j.tet.2018.02.040
Abstract: Abstract We discovered asymmetric autocatalysis in the enantioselective addition of diisopropylzinc to pyrimidine-5-carbaldehyde, where the product 5-pyrimidyl alkanol acts as a highly efficient asymmetric autocatalyst to afford more of itself (Soai reaction). Asymmetric autocatalysis proceeded… read more here.
Keywords: chirality; self replication; asymmetric autocatalysis; autocatalysis ... See more keywords