A broader active site in Pyrococcus horikoshii CoA disulfide reductase accommodates larger substrates and reveals evidence of subunit asymmetry
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DOI: 10.1002/2211-5463.12439
Abstract: Within the family of pyridine nucleotide disulfide oxidoreductase (PNDOR), enzymes are a group of single‐cysteine containing FAD‐dependent reductases that utilize a tightly bound coenzyme A to assist in the NAD(P)H‐dependent reduction of di‐, per‐, and… read more here.
Keywords: pyrococcus horikoshii; coa disulfide; disulfide reductase; coa ... See more keywords
Crystal structure of a novel type of ornithine δ-aminotransferase from the hyperthermophilic archaeon Pyrococcus horikoshii.
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DOI: 10.1016/j.ijbiomac.2022.03.114
Abstract: Ornithine δ-aminotransferase (Orn-AT) activity was detected for the enzyme annotated as a γ-aminobutyrate aminotransferase encoded by PH1423 gene from Pyrococcus horikoshii OT-3. Crystal structures of this novel archaeal ω-aminotransferase were determined for the enzyme in… read more here.
Keywords: plp; aminotransferase; pyrococcus horikoshii; ornithine aminotransferase ... See more keywords