Articles with "pyrophosphate depletion" as a keyword



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Geranylgeranyl pyrophosphate depletion by statins compromises skeletal muscle insulin sensitivity

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Published in 2022 at "Journal of Cachexia, Sarcopenia and Muscle"

DOI: 10.1002/jcsm.13061

Abstract: Statins are widely prescribed cholesterol‐lowering drugs but have been shown to increase the risk of type 2 diabetes mellitus. However, the molecular mechanisms underlying the diabetogenic effect of statins are still not fully understood. read more here.

Keywords: pyrophosphate depletion; statins compromises; geranylgeranyl pyrophosphate; depletion statins ... See more keywords