A Dual‐Locked Tandem Fluorescent Probe for Imaging of Pyroptosis in Cancer Chemo‐Immunotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202206510
Abstract: Real‐time imaging of programmed cancer cell death (PCD) is imperative to monitor cancer therapeutic efficacy and tailor therapeutic regimens; however, specific in vivo detection of intratumoral pyroptosis remains challenging. Herein, a dual‐locked and tandem activatable… read more here.
Keywords: pyroptosis cancer; pyroptosis; cancer chemo; cancer ... See more keywords
Role of pyroptosis in cancer cells and clinical applications.
Sign Up to like & getrecommendations! Published in 2021 at "Biochimie"
DOI: 10.1016/j.biochi.2021.03.007
Abstract: Chemotherapy drugs usually inhibit tumor cell growth through the apoptosis pathway. However, tumor cells become resistant to chemotherapy drugs by evading apoptosis. It is necessary to find new ways to inhibit tumor growth through other… read more here.
Keywords: pyroptosis cancer; pyroptosis; role pyroptosis; role ... See more keywords
Photocatalytic Superoxide Radical Generator that Induces Pyroptosis in Cancer Cells.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c03256
Abstract: Pyroptosis, a newly characterized form of immunogenic cell death, is attracting increasing attention as a promising approach to cancer immunotherapy. However, biocompatible strategies to activate pyroptosis remain rare. Here, we show that a photocatalytic superoxide… read more here.
Keywords: pyroptosis cancer; cancer; radical generator; pyroptosis ... See more keywords
USP48 stabilizes gasdermin E to promote pyroptosis in cancer.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer research"
DOI: 10.1158/0008-5472.can-22-1812
Abstract: Pyroptosis is a type of programmed cell death characterized by the activation of inflammatory caspases and the cleavage of gasdermin proteins. Pyroptosis can suppress tumor development and induce anti-tumor immunity, and activating pyroptosis is a… read more here.
Keywords: pyroptosis cancer; stabilizes gasdermin; pyroptosis; usp48 stabilizes ... See more keywords
Noncoding RNAs in pyroptosis and cancer progression: Effect, mechanism, and clinical application
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.982040
Abstract: Cell death is generally classified into two categories: regulated cell death (RCD) and accidental cell death (ACD). In particular, RCD is a kind of genetically controlled process, including programmed apoptotic death and programmed necrotic death.… read more here.
Keywords: cell death; rnas pyroptosis; pyroptosis cancer; pyroptosis ... See more keywords