Platelet-derived microparticles stimulated by anti-β2GPI/β2GPI complexes induce pyroptosis of endothelial cells in antiphospholipid syndrome.
Sign Up to like & getrecommendations! Published in 2022 at "Platelets"
DOI: 10.1080/09537104.2022.2156492
Abstract: Platelet microparticles (PMPs) are vesicles that are released by platelets into the extracellular space and play a role in antiphospholipid antibody syndromes. PMPs have recently been recognized as a new and viable cell. There is… read more here.
Keywords: endothelial cells; pyroptosis endothelial; 2gpi complexes; 2gpi 2gpi ... See more keywords
The role of pyroptosis in endothelial dysfunction induced by diseases
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DOI: 10.3389/fimmu.2023.1093985
Abstract: Most organs in the body rely on blood flow, and vesicular damage is the leading cause of injury in multiple organs. The endothelium, as the barriers of vessels, play a critical role in ensuring vascular… read more here.
Keywords: pyroptosis endothelial; role; dysfunction induced; pyroptosis ... See more keywords
Salvianolic acid A regulates pyroptosis of endothelial cells via directly targeting PKM2 and ameliorates diabetic atherosclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.1009229
Abstract: Rescuing endothelial cells from pyroptotic cell death emerges as a potential therapeutic strategy to combat diabetic atherosclerosis. Salvianolic acid A (SAA) is a major water-soluble phenolic acid in the Salvia miltiorrhiza Bunge, which has been… read more here.
Keywords: endothelial cells; pkm2; diabetic atherosclerosis; pyroptosis endothelial ... See more keywords